Methyl-tert butyl ether or MTBE is a fuel oxygenate that is added to gasoline to promote the more efficient and cleaner burning of gas, thereby leading to improved air quality. Recently, MTBE has been detected in lakes, reservoirs and groundwater used as drinking water supplies and in some cases concentrations have exceeded the action levels for both taste & odor and human health. A multi-disciplinary team of fifteen faculty have developed an integrated workplan which focuses on MTBE in aquatic environments. The focus of this work will be at a state-wide scale and investigates a wide variety of topics related to surface water and groundwater supplies. Major categories include: (a) analysis of current levels of MTBE in drinking water supplies; (b) sources of MTBE to surface water bodies, groundwater and coastal waters and the effects of oxygenates on under-ground storage tanks; (c) factors regulating environmental transport and fate; (d) environmental toxicity and risk assessment, (e) control options and costs, and (f) evaluation of technical and policy options, conclusions and recommendations. In addition, the impact(s) of MTBE on the Lake Tahoe environment will also be addressed as stipulated in SB 521. We are conducting an integrative review of the existing literature, assessment of available monitoring data, treatment technologies, and original research. The Governor, State law-makers, applicable regulatory agencies and ultimately the public will be able to use the SB 521 final project report for guidance on both the need and the options for taking appropriate protective and remedial actions.